| Gene Symbol | SCARB2 |
| Function | SCARB2/LIMP-2 encodes a highly glycosylated type I transmembrane protein that serves multiple functions: |
| Subcellular Localization | - Lysosomal membranes |
| Pathways | Autophagy, Mitochondrial Function, Mtor, Cholesterol, Alpha-Synuclein |
| GeneCards | SCARB2 |
| Human Protein Atlas | SCARB2 |
| Dementia with Lewy Bodies | Risk variant carriers show Lewy body pathology |
| Multiple System Atrophy | Possible lysosomal involvement |
| Gaucher Disease | LIMP-2 deficiency exacerbates GCase dysfunction |
| Associated Diseases | Als, Ms, REM sleep behavior disorder, Synucleinopathy |
| Known Drugs/Compounds | Glutathione |
| Interactions | A2M, Actin, AGING, ALPHA-SYNUCLEIN, ARF1, BCHE |
| KG Connections | 97 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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