| Gene Symbol | GLI2 |
| Full Name | GLI Family Zinc Finger 2 |
| Chromosome | 2q14.2 |
| Protein Type | Transcription Factor |
| Function | encodes a 1586 amino acid zinc finger transcription factor that functions as the primary transcriptional activator of the Hedgehog (Hh) signaling pathway. |
| Primary Expression | the ventral neural tube floor plate, where it is essential for specification of ventral cell fates including dopaminergic progenitors of the midbrain |
| Amino Acids | 1586 aa |
| Exons | 13 |
| Pathways | Apoptosis, Hedgehog |
| Ensembl ID | ENSG00000074047 |
| GeneCards | GLI2 |
| Human Protein Atlas | GLI2 |
| Associated Diseases | neurodegeneration |
| Known Drugs/Compounds | rapamycin |
| Interactions | APOPTOSIS, BCL2, CANCER, FKBP5, GAPDH, GFAP |
| KG Connections | 30 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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