gene 1,438 words KG: GAS6
Contents

GAS6 - Growth Arrest Specific 6

🧬 Gene Info
Gene SymbolGAS6
Full NameGrowth Arrest Specific 6
Chromosome13q34
Functionis a multifunctional protein involved in cell survival, proliferation, migration, phagocytosis, and immunomodulation.
PathwaysNf-Κb, Phagocytosis, Proteasome
UniProt ID[P14384](https://www.uniprot.org/uniprot/P14384)
Ensembl IDENSG00000111321
OMIM600441
GeneCardsGAS6
Human Protein AtlasGAS6
Associated DiseasesAging, Alzheimer, APOPTOSIS, Atherosclerosis, Cancer, Ms
InteractionsABCA1, ABCA7, ABCG1, ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID
KG Connections113 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (17)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.38
TREM2-Dependent Microglial Senescence Transition
Score: 0.95
Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.91
APOE-Dependent Autophagy Restoration
Score: 0.85
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79

Related Analyses (7)

What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Cell type vulnerability in Alzheimer's Disease (SEA-AD data
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Cell type vulnerability in Alzheimer's Disease (SEA-AD data)
neurodegeneration · archived

See Also (7)

Astrocytes
cell · KG edge: associated_with
Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: activates
Astrocytes
entity · KG edge: associated_with
AXL - AXL Receptor Tyrosine Kinase
gene · KG edge: activates
APP Gene Dosage Reduction Therapy for Down Syndrome
idea · KG edge: activates

Knowledge Graph (12 edges)

GAS6 inhibits APOE
GAS6 inhibits TRAF6
TAU activates GAS6
SIRT1 activates GAS6
GAS6 associated_with UBIQUITIN
GAS6 activates APP
GAS6 activates AXL
AXL associated_with GAS6
GAS6 associated_with AXL
AXL interacts_with GAS6

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