gene 924 words KG: ELAVL2
Contents

ELAVL2 Gene

🧬 Gene Info
Gene SymbolELAVL2
Full NameELAV Like RNA Binding Protein 2
Chromosome9p21.3
Protein FamilyELAVL (Embryonic Lethal, Abnormal Vision, Drosophila-like)
FunctionELAVL2 is a member of the ELAVL family (ELAVL1-4) that is expressed specifically in neurons and primarily localizes to the cytoplasm.
Subcellular Localizationof specific mRNAs within neurons, enabling localized protein synthesis at synapses
Molecular Weight39 kDa
PathwaysCholesterol, Lipid Metabolism, Neurogenesis, Translation Fidelity
GeneCardsELAVL2
Human Protein AtlasELAVL2
Associated DiseasesAging, Als, Ftd, Neurodegeneration
InteractionsBRAIN INJURY, FN1, FUS, GFAP, IGF2BP1, METTL3
KG Connections184 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (10)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Autophagosome Maturation Checkpoint Control
Score: 0.71
SASP-Mediated Complement Cascade Amplification
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Cross-Seeding Prevention Strategy
Score: 0.69
Glycine-Rich Domain Competitive Inhibition
Score: 0.64
Cryptic Exon Silencing Restoration
Score: 0.53
RNA-Binding Competition Therapy for TDP-43 Cross-Seeding
Score: 0.47

Related Analyses (4)

Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (7)

Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: associated_with
BDNF Gene
gene · KG edge: associated_with
C1QA Gene — Complement Component 1q A Chain
gene · KG edge: associated_with
CD44 - Cell Surface Glycoprotein
gene · KG edge: associated_with
CLPP (Caseinolytic Mitochondrial Matrix Peptidase Prote
gene · KG edge: associated_with

Knowledge Graph (12 edges)

ELAVL2 therapeutic_target C1Q
ELAVL2 therapeutic_target MTOR
ELAVL2 therapeutic_target CLPP
ELAVL2 therapeutic_target RAB11
ELAVL2 therapeutic_target STX17
ELAVL2 therapeutic_target RAB5
ELAVL2 therapeutic_target SNAP29
ELAVL2 therapeutic_target IGF2BP1
ELAVL2 therapeutic_target LONP1
ELAVL2 therapeutic_target BDNF

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