| Gene Symbol | BMPR1A |
| Full Name | Bone Morphogenetic Protein Receptor Type 1A |
| Chromosome | 10q22.3 |
| Protein Type | Serine/Threonine Kinase |
| Function | Upon ligand binding, BMPR1A forms a heteromeric complex with type II receptors (BMPR2, ACVR2A, ACVR2B) [1]. |
| Molecular Weight | 60 kDa |
| Amino Acids | 532 aa |
| Pathways | BMP signaling |
| Ensembl ID | ENSG00000107779 |
| GeneCards | BMPR1A |
| Human Protein Atlas | BMPR1A |
| Extracellular domain | Ligand-binding region with cysteine-rich motifs |
| Transmembrane domain | Single-pass membrane anchor |
| MAPK pathways | Activation of ERK, JNK, and p38 MAPK |
| PI3K/AKT pathway | Pro-survival signaling |
| Associated Diseases | demyelination, neurodegeneration |
| Interactions | ATG5, AUTOPHAGY, BMP2, BMPR2, FAM134C, FGFR3 |
| KG Connections | 29 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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