| Gene Symbol | RETREG3 |
| Full Name | Reticulophagy Regulator 3 |
| Chromosome | 5q31.1 |
| Function | is a critical endoplasmic reticulum (ER)-resident protein that functions as an autophagy receptor mediating reticulophagy—the selective degradation of ER components through the autophagy-lysosome p... |
| Subcellular Localization | . This region shows less conservation compared to RETREG1, suggesting possible functional divergence between the two par |
| Molecular Weight | 48 kDa |
| Amino Acids | 449 aa |
| Exons | 7 |
| UniProt ID | Q8N6I6 |
| NCBI Gene ID | 642473 |
| Ensembl ID | ENSG00000175318 |
| GeneCards | RETREG3 |
| Human Protein Atlas | RETREG3 |
| Sumoylation | Functional studies suggest SUMO modification of RETREG3 under stress conditions, potentially regulating its oligomerization state [5]. |
| Associated Diseases | Parkinson's Disease, Alzheimer's Disease |
| Interactions | AUTOPHAGY, LC3 |
| KG Connections | 5 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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