gene 648 words KG: BAG1
Contents

BAG1 Gene

🧬 Gene Info
Gene SymbolBAG1
Full NameBCL2-Associated Athanogene 1
Chromosome9p12
Protein TypeChaperone
FunctionBAG1 is a co-chaperone that modulates Hsp70/Hsc70 function
Primary Expressionvarious cancers
Molecular Weight46 kDa
Amino Acids110 aa
PathwaysMAPK
UniProt IDO95351
NCBI Gene ID573
GeneCardsBAG1
Human Protein AtlasBAG1
Associated Diseasesneurodegeneration
InteractionsAPOPTOSIS, ATP, DNAJB6, HSP40, HSP70, HSPA1A
KG Connections48 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (5)

CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Chaperone-Mediated APOE4 Refolding Enhancement
Score: 0.68
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
HSP70 Co-chaperone DNAJB6 Universal Cross-Seeding Inhibitor
Score: 0.54

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed

See Also (13)

Astrocytes
cell · KG edge: expressed_in
Apoptosis in Neurodegeneration
entity · KG edge: regulates
Astrocytes
entity · KG edge: expressed_in
Complement System Dysregulation in Neurodegeneration -
gap · KG edge: regulates
DISC1 — Disrupted in Schizophrenia 1
gene · KG edge: associated_with

Knowledge Graph (12 edges)

ICAM1 inhibits BAG1
BAG1 inhibits SOD1
BAG1 expressed_in KIF3B
NBN regulates BAG1
SGK3 regulates BAG1
TNF associated_with BAG1
SLC24A2 regulates BAG1
DNAJC2 associated_with BAG1
CHMP3 regulates BAG1
PDE4C regulates BAG1

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