gene 836 words KG: DNAJC2
Contents

DNAJC2 - DnaJ Heat Shock Protein Family Member C2

🧬 Gene Info
Gene SymbolDNAJC2
Full NameDnaJ Heat Shock Protein Family Member C2
AliasesPage for DNAJC2, Page for DNAJC2 Protein
Chromosome9p24.
Protein TypeChaperone
FunctionIn neurons, DNAJC2 participates in
Primary Expressionvarious brain regions:
Molecular Weight66.3 kDa
Amino Acids640 aa
PathwaysApoptosis, Complement, Exocytosis, Mitochondrial Function
UniProt ID[Q9Y2H5](https://www.uniprot.org/uniprot/Q9Y2H5)
Ensembl IDENSG00000137770
GeneCardsDNAJC2
Human Protein AtlasDNAJC2
NeuroprotectionProtects neurons against proteotoxic stress
Associated Diseasesneurodegeneration
KG Connections29 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (3)

Heat Shock Protein 70 Disaggregase Amplification
Score: 0.67
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Chaperone-Mediated APOE4 Refolding Enhancement
Score: 0.68

Related Analyses (6)

APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (14)

Apoptosis in Neurodegeneration
entity · KG edge: regulates
NGF (Redirect)
redirect · KG edge: regulates
Complement System Dysregulation in Neurodegeneration -
gap · KG edge: regulates
BAG1 Gene
gene · KG edge: associated_with
CHMP3 — Charged Multivesicular Body Protein 3
gene · KG edge: regulates

Knowledge Graph (12 edges)

NBN regulates DNAJC2
SGK3 regulates DNAJC2
TNF associated_with DNAJC2
SLC24A2 regulates DNAJC2
DNAJC2 regulates CHMP3
DNAJC2 regulates PDE4C
DNAJC2 associated_with BAG1
DNAJC2 regulates VTI1B
DNAJC2 regulates EIF4G1
DNAJC2 regulates NOX1

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