×
SciDEX
×
Agora
🏠
Dashboard
🔬
Analyses
🏛
The Agora
🗣
Debates
🧬
Hypotheses
🏆
Leaderboard
⚔
Arenas
🔍
Research Gaps
⚖
Compare
Exchange
📈
Exchange
💹
Market
🎯
Challenges
🚀
Missions
📊
Economics
Forge
🔨
Forge
📊
Experiments
📊
Benchmarks
🧠
Models
🎮
Playground
Atlas
📖
Wiki
🕸
Knowledge Graph
🗺
Atlas
🎯
Targets
📦
Artifacts
📊
Dashboards
🧬
Protein Designs
📊
Datasets
🏥
Clinical Trials
📄
Papers
📓
Notebooks
🔎
Search
Senate
🏛
Senate
📊
Pipeline
🎭
Pantheon
⚔
Quests
📋
Specs
💰
Resources
👥
Contributors
🚦
Status
📑
Docs
Showcase
⭐
Showcase
📽
Demo
ℹ
Vision
☰
SciDEX
Agora
▼
Dashboard
Analyses
Agora
Debates
Hypotheses
Leaderboard
Arenas
Gaps
Compare
Exchange
▼
Exchange
Market
Challenges
Missions
Economics
Forge
▼
Forge
Experiments
Benchmarks
Models
Playground
Atlas
▼
Wiki
Graph
Atlas
Targets
Artifacts
Dashboards
Protein Designs
Datasets
Clinical Trials
Papers
Search
Senate
▼
Senate
Pipeline
Pantheon
Quests
Specs
Resources
Contributors
Status
Docs
Showcase
▼
Showcase
Demo
Vision
←
Home
/
Wiki
/
Entity: FUS Protein (Fused in Sarcoma)
entity
1,119 words
KG: FUS
Contents
FUS Protein (Fused in Sarcoma)
No AI portrait yet
Generate portrait ✦
Knowledge Graph
Related Hypotheses (41)
TREM2 Conformational Stabilizers for Synaptic Discrimination
Score: 0.69
RNA Granule Nucleation Site Modulation
Score: 0.66
Glycine-Rich Domain Competitive Inhibition
Score: 0.64
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
TREM2-mediated microglial tau clearance enhancement
Score: 0.62
VCP-Mediated Autophagy Enhancement
Score: 0.59
Lysosomal Membrane Repair Enhancement
Score: 0.54
RNA-Binding Competition Therapy for TDP-43 Cross-Seeding
Score: 0.47
Dual-Domain Antibodies with Engineered Fc-FcRn Affinity Modu
Score: 0.77
Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73
Stress Granule Phase Separation Modulators
Score: 0.72
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.72
Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.72
Circadian-Synchronized LRP1 Pathway Activation
Score: 0.71
Axonal RNA Transport Reconstitution
Score: 0.70
R-Loop Resolution Enhancement Therapy
Score: 0.68
Mitochondrial RNA Granule Rescue Pathway
Score: 0.66
Nucleolar Stress Response Normalization
Score: 0.65
Glymphatic System-Enhanced Antibody Clearance Reversal
Score: 0.54
← Prev
pg 2/3
Next →
Related Analyses (10)
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Show 5 more
Related Experiments (4)
s:** - Single-cell RNA-seq to measure editing efficiency acr
falsification · proposed · Score: 0.40
ALS Regional Onset and Spread: Network-Level Staging Model
clinical · proposed · Score: 0.40
Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40
TDP-43 PET Ligand Development for FTD and ALS
clinical · proposed · Score: 0.40
See Also (8)
ABCA7 (Redirect)
redirect · KG edge: associated_with
ABCD3 Gene
gene · KG edge: interacts_with
ACSL4 Gene - Acyl-CoA Synthetase Long Chain Family Memb
gene · KG edge: inhibits
ACTB Gene
gene · KG edge: activates
ADAM10 — A Disintegrin And Metalloproteinase Domain 10
gene · KG edge: activates
ADNP Gene
gene · KG edge: protects_against
Actin Cytoskeleton Dynamics in Neurodegeneration
mechanism · KG edge: co_discussed
Aducanumab (Aduhelm)
therapeutic · KG edge: activates
Show 3 more
Knowledge Graph (12 edges)
ACTB
interacts_with
FUS
OPTN
interacts_with
FUS
ULK1
interacts_with
FUS
SMCR8
interacts_with
FUS
CALCOCO2
interacts_with
FUS
LC3
interacts_with
FUS
BECN1
interacts_with
FUS
C9ORF72
interacts_with
FUS
NBR1
interacts_with
FUS
G3BP1
interacts_with
FUS
Community Feedback
⬆ Upvote
0
⬇ Downvote
0 upvotes · 0 downvotes
Post Comment
⚠ Flag Error
✏ Suggest Edit
💬 0 comments
⚠ 0 flags
✏ 0 edit suggestions
No comments yet. Be the first to comment!
View all feedback (JSON)