gene 916 words KG: ADNP
Contents

ADNP Gene

🧬 Gene Info
Gene SymbolADNP
Protein TypeTranscription Factor
FunctionADNP encodes a 1,102 amino acid protein containing a homeobox domain, nine zinc fingers, and a PxVxL motif that mediates interaction with the SWI/SNF chromatin remodeling complex through HP1.
Molecular Weight124 kDa
Amino Acids102 aa
PathwaysAutophagy, Epigenetic, Wnt
Ensembl IDENSG00000101126
GeneCardsADNP
Human Protein AtlasADNP
Associated DiseasesAging, autism spectrum disorder, Ms
InteractionsALZHEIMER, ALZHEIMER'S DISEASE, APC, App, APP, APP/PS1
KG Connections83 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (13)

Synaptic Vesicle Tau Capture Inhibition
Score: 0.58
Trans-Synaptic Adhesion Molecule Modulation
Score: 0.54
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Cross-Seeding Prevention Strategy
Score: 0.69
Lysosomal Positioning Dynamics Modulation
Score: 0.69
Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.67
Glycine-Rich Domain Competitive Inhibition
Score: 0.64
Quantum Coherence Disruption in Cellular Communication
Score: 0.63
Tau-Independent Microtubule Stabilization via MAP6 Enhanceme
Score: 0.57
Cryptic Exon Silencing Restoration
Score: 0.53
RNA-Binding Competition Therapy for TDP-43 Cross-Seeding
Score: 0.47

Related Analyses (6)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Epigenetic reprogramming in aging neurons
neurodegeneration · archived

See Also (9)

Astrocytes
cell · KG edge: inhibits
blarcamesine-axon
clinical_trial · KG edge: inhibits
Astrocytes
entity · KG edge: inhibits
astrocyte-neuron-metabolic-coupling-parkinsons
general · KG edge: expressed_in
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: interacts_with

Knowledge Graph (12 edges)

YY1 associated_with ADNP
HDAC2 associated_with ADNP
LAMP1 associated_with ADNP
ADNP associated_with BECN1
ADNP interacts_with SIRT1
ADNP associated_with LC3
ADNP interacts_with TAU
ADNP interacts_with LC3
ADNP inhibits P2X7
SIRT1 interacts_with ADNP

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