gene 1,174 words KG: CKAP4
Contents

CKAP4 — Cytoskeleton-Associated Protein 4

🧬 Gene Info
Gene SymbolCKAP4
Full NameCytoskeleton-Associated Protein 4
Chromosome12p13.1
Functionis a type II transmembrane protein localized to the endoplasmic reticulum (ER), ER-Golgi intermediate compartment (ERGIC), and nuclear envelope.
Primary Expressionthe brain, particularly in motor neurons of the spinal cord and motor cortex
Subcellular Localizationthe endoplasmic reticulum (ER), ER-Golgi intermediate compartment (ERGIC), and nuclear envelope. The protein plays criti
Molecular Weight63 kDa
Amino Acids400 aa
PathwaysWnt signaling
UniProt IDQ07011
NCBI Gene ID10527
Ensembl IDENSG00000129195
OMIM616404
GeneCardsCKAP4
Human Protein AtlasCKAP4
Associated DiseasesAlzheimer's Disease, Cancer
InteractionsADAM15, Akt, AKT, AND, AUTOPHAGY, HIF
KG Connections49 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Knowledge Graph (12 edges)

CKAP4 activates RANBP2
CKAP4 activates NBR1
CKAP4 activates AKT
CKAP4 regulates FAM134B
RANBP2 activates CKAP4
NBR1 activates CKAP4
FAM134B regulates CKAP4
AKT activates CKAP4
CKAP4 activates Rb
CKAP4 activates ADAM15

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