| Gene Symbol | ADAM15 |
| Full Name | ADAM metallopeptidase domain 15 |
| Aliases | A Disintegrin and Metalloproteinase 15 |
| Chromosome | 1q21.3 |
| Function | is a member of the ADAM family of transmembrane metalloproteinases that plays important roles in cell adhesion, proteolysis, and signaling. |
| Primary Expression | various tissues including the brain, where it participates in neuronal function and neuroinflammation |
| Molecular Weight | 87.8 kDa |
| Pathways | Notch |
| UniProt ID | Q13487 |
| NCBI Gene ID | 8750 |
| Ensembl ID | ENSG00000145040 |
| OMIM | 605527 |
| GeneCards | ADAM15 |
| Human Protein Atlas | ADAM15 |
| Metalloproteinase activity | Cleaves various substrates including adhesion molecules, growth factors, and amyloid precursor protein (APP) |
| Associated Diseases | ALS, Alzheimer's disease, Parkinson's disease |
| Interactions | Akt, CKAP4, MMP9, PI3K, RNA |
| KG Connections | 20 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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