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mechanism 4,156 words KG: CREB
Contents

CREB Signaling in Neurodegeneration

⚙ Mechanism Info
NameCREB
Key Genes/ProteinsABETA, ACAT1, ACETYL-COA, ACHE, ACOX1, Actin
Related DiseasesAging
Linked Hypotheses6 hypotheses

No AI portrait yet

Knowledge Graph

Related Hypotheses (12)

Gamma Oscillation Entrainment Enhances lncRNA-9969-Mediated
Score: 0.84LPS-primed microglial trained immunity establishes persisten
Score: 0.67Epigenetic Memory Reprogramming for Alzheimer's Disease
Score: 0.61Activity-Dependent Synaptic Tagging via CREB-BDNF-TrkB Signa
Score: 0.61Gamma-Entrained PV Interneuron Networks Enable Precision p-t
Score: 0.54Gamma-Entrained PV Interneurons Enable p-tau217-Guided Preci
Score: 0.545-HT2A/C Silencing Enables Sustained BDNF-TrkB Signaling for
Score: 0.52Alpha-Beta Oscillation Coupling Enhances lncRNA-9969-Mediate
Score: 0.47Alpha-Beta Oscillation Entrainment Enhances lncRNA-9969-Medi
Score: 0.45Alpha-Theta Oscillation Modulation Enhances lncRNA-9969-Medi
Score: 0.45Theta-Gamma Coupling Modulates lncRNA-9969-Mediated Mitochon
Score: 0.44cAMP/PKA-Dependent Transcription Factor Activation via Nutri
Score: 0.42

Knowledge Graph (12 edges)

ALS associated_with CREB
CREB associated_with frontotemporal dementia
CREB associated_with NLRP3
CREB interacts_with PI3K
CREB interacts_with PKA
CREB interacts_with ERK
CREB regulates BDNF
cAMP activates CREB
CREB regulates BDNF_GENE
CREB activates BDNF_MRNA

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