gene 2,879 words KG: CD33
Contents

CD33 — Cluster of Differentiation 33

🧬 Gene Info
Gene SymbolCD33
Full NameCluster of Differentiation 33
AliasesSiglec-3
Chromosome19q13.41
FunctionSialic acid binding: Recognizes α2,6-linked sialic acids on glycoproteins
Molecular Weight67 kDa
Amino Acids354 aa
Exons7
PathwaysApoptosis, Autophagy, Blood-Brain Barrier, Dysbiosis, Epigenetic
UniProt ID[P20138](https://www.uniprot.org/uniprot/P20138)
GeneCardsCD33
Human Protein AtlasCD33
Associated DiseasesAging, Als, Alzheimer, Alzheimer's disease
Known Drugs/CompoundsStem Cell Therapy
InteractionsABCA7, Actin, ALZHEIMER, ALZHEIMER DISEASE, ALZHEIMER'S DISEASE, AMYLOID
SciDEX HypothesesCD33-Dependent Switch Hypothesis: CD33 Antagonism
KG Connections657 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (1)

CD33-Dependent Switch Hypothesis: CD33 Antagonism Redirects
Score: 0.52

Knowledge Graph (12 edges)

TYROBP interacts_with CD33
TYROBP associated_with CD33
APP interacts_with CD33
PSEN1 interacts_with CD33
CD33 interacts_with OVERVIEW
CD33 interacts_with PSEN1
CD33 inhibits BCL2
APP activates CD33
CD33 activates OVERVIEW
CD33 activates PSEN1

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