Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about GLUCOSE UPTAKE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | GLUCOSE UPTAKE |
graph TD
GLUCOSE_UPTAKE[GLUCOSE UPTAKE]
GLUCOSE_UPTAKE -->|expressed in| MUSCLE[MUSCLE]
TUG[TUG] -->|regulates| GLUCOSE_UPTAKE
Insulin_Stimulated_TUG_Cleavag[Insulin-Stimulated TUG Cleavage] -->|upregulates| GLUCOSE_UPTAKE
ASPSCR1[ASPSCR1] -->|promotes| GLUCOSE_UPTAKE
SLC2A4[SLC2A4] -->|mediates| GLUCOSE_UPTAKE
SLC2A1[SLC2A1] -->|promotes| GLUCOSE_UPTAKE
SLC2A3[SLC2A3] -->|promotes| GLUCOSE_UPTAKE
Insulin[Insulin] -->|regulates| GLUCOSE_UPTAKE
INS[INS] -->|activates| GLUCOSE_UPTAKE
Tug_Cleavage[Tug Cleavage] -->|regulates| GLUCOSE_UPTAKE
AKT2[AKT2] -->|promotes| GLUCOSE_UPTAKE| Target | Relation | Type | Str |
|---|---|---|---|
| MUSCLE | expressed_in | entity | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| ASPSCR1 | promotes | protein | 0.95 |
| TUG | regulates | protein | 0.95 |
| Insulin-Stimulated TUG Cleavage | upregulates | pathway | 0.95 |
| Tug Cleavage | regulates | process | 0.90 |
| SLC2A4 | mediates | protein | 0.90 |
| SLC2A1 | promotes | gene | 0.90 |
| SLC2A3 | promotes | gene | 0.90 |
| TUG cleavage | regulates | biological_process | 0.90 |
| INS | activates | entity | 0.90 |
| Insulin | regulates | entity | 0.90 |
| AKT2 | promotes | gene | 0.88 |
| ERK | regulates | protein | 0.85 |
| IRS2 | involved_in | gene | 0.85 |
| SDHHQ | regulates | drug | 0.85 |
| GSK3B | regulates | gene | 0.80 |
| NF-κB | associated_with | pathway | 0.80 |
| PI3K | regulates | entity | 0.80 |
| Akt | regulates | protein | 0.70 |
| BMAL1 | modulates | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning GLUCOSE UPTAKE in their description or question text
No additional research found