gene

SYT4

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SYT4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

15Connections

0Hypotheses

0Analyses

9Outgoing

6Incoming

0Experiments

0Debates

Summary

Page for SYT4 — Synaptotagmin

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🧬 Gene Info

Gene Symbol	SYT4
Full Name	Synaptotagmin
Chromosome	18q12.3
Function	is a member of the synaptotagmin family of calcium-binding proteins that regulate neurotransmitter release at synapses [1].
Pathways	Mapk, Synaptic Plasticity
UniProt ID	Q9H0Y5
NCBI Gene ID	6860
Ensembl ID	ENSG00000124614
GeneCards	SYT4
Human Protein Atlas	SYT4
Associated Diseases	neurodegeneration
Interactions	APOER2, BDNF, ERK1/2, HTT, HUNTINGTIN, ITSN1
KG Connections	15 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: SYT4 — AlphaFold Q9H0Y5 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

SYT4 — Synaptotagmin

gene · 568 words

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Pathway Diagram

graph TD
    SYT4["SYT4"]
    SYT4 -->|"activates"| Als["Als"]
    SYT4 -->|"activates"| Depression["Depression"]
    SYT4 -->|"activates"| HUNTINGTIN["HUNTINGTIN"]
    SYT4 -->|"activates"| ERK1_2["ERK1/2"]
    SYT4 -->|"activates"| MAPK["MAPK"]
    SYT4 -->|"activates"| ITSN1["ITSN1"]
    SYT4 -->|"activates"| Mapk["Mapk"]
    SYT4 -->|"activates"| Synaptic_Plasticity["Synaptic Plasticity"]
    REELIN["REELIN"] -->|"activates"| SYT4
    APOER2["APOER2"] -->|"activates"| SYT4
    SRC["SRC"] -->|"activates"| SYT4
    BDNF["BDNF"] -->|"activates"| SYT4
    HTT["HTT"] -->|"activates"| SYT4

Outgoing (9)

Target	Relation	Type	Str
Depression	activates	disease	0.65
Als	activates	disease	0.65
MAPK	activates	gene	0.60
ITSN1	activates	gene	0.60
Mapk	activates	pathway	0.60
Synaptic Plasticity	activates	pathway	0.60
HUNTINGTIN	activates	gene	0.60
Neuron	activates	cell_type	0.60
ERK1/2	activates	gene	0.60

Incoming (6)

Source	Relation	Type	Str
genes-syt4	linked_to	wiki	1.00
REELIN	activates	gene	0.60
SRC	activates	gene	0.60
BDNF	activates	gene	0.60
HTT	activates	gene	0.60
APOER2	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning SYT4 in their description or question text

No additional research found