Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about progressive-supranuclear-palsy: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
flowchart TD
N0["PROGRESSIVE SUPRANUCLEAR PALSY"]
N1["INFLAMMATION"]
N0 -->|"regulates"| N1
N2["TAU"]
N2 -->|"produces"| N0
N3["MAPT"]
N0 -->|"associated with"| N3
N4["AQP4"]
N0 -->|"associated with"| N4
N5["APP"]
N0 -->|"associated with"| N5
N6["TH"]
N0 -->|"associated with"| N6
N7["HDAC3"]
N0 -->|"associated with"| N7
N8["BRD4"]
N0 -->|"associated with"| N8
N9["TDP-43"]
N0 -->|"associated with"| N9
classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
classDef therapeutic fill:#1a2a2a,stroke:#26a69a,color:#e0e0e0
class N2 protein
class N3 gene
class N4 gene
class N5 gene
class N6 gene
class N7 gene
class N8 gene
class N9 gene| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| entities-biiib080 | associated_with | wiki | 0.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning progressive-supranuclear-palsy in their description or question text
No additional research found