ICAM5

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolICAM5
Nameintercellular adhesion molecule 5
Typeprotein-coding
Sourcemygene

Summary

The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-

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