gene 1,335 words KG: ABCG4
Contents

ABCG4 Gene — ATP-Binding Cassette Subfamily G Member 4

🧬 Gene Info
Gene SymbolABCG4
Full NameABCG4 — ATP-Binding Cassette Subfamily G Member 4
AliasesATP-Binding Cassette Subfamily G Member 4
Chromosome11q22.3
Protein TypeGene
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionthe brain and is involved in cholesterol and lipid transport, with emerging roles in neurodegenerative disease pathogenesis
Molecular Weight71 kDa
Amino Acids646 aa
Exons13
GeneCardsABCG4
Human Protein AtlasABCG4
Associated Diseasesneurodegeneration
InteractionsRas
KG Connections28 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (11)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
Membrane Cholesterol Gradient Modulators
Score: 0.71
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79
Competitive APOE4 Domain Stabilization Peptides
Score: 0.78

Related Analyses (7)

Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed

Related Experiments (2)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Synaptic Mitochondrial Resilience Enhancement for Parkinson'
validation · proposed · Score: 0.40

See Also (14)

Astrocytes
cell · KG edge: regulates
Hippocampal CA1 Pyramidal Neurons
cell · KG edge: expressed_in
ATP P2X3 Receptor Neurons
cell · KG edge: regulates
NeuRon Therapeutics
company · KG edge: activates
Neurodegeneration
disease · KG edge: implicated_in

Knowledge Graph (12 edges)

ABCG1 regulates ABCG4
APOE regulates ABCG4
ABCG4 regulates ABCA1
ABCA1 regulates ABCG4
ABCG4 regulates ABCG1
ABCG4 regulates APOE
genes-abcg4 describes ABCG4
ATP regulates ABCG4
ALZHEIMER regulates ABCG4
ASTROCYTES regulates ABCG4

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)