Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about AMYLOID-BETA-PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | AMYLOID |
| Full Name | BETA-PROTEIN |
| GeneCards | AMYLOID |
| Human Protein Atlas | AMYLOID |
| Associated Diseases | Aging, Als, Alzheimer, Alzheimer Disease, ALZHEIMER'S DISEASE |
| Known Drugs/Compounds | DONANEMAB, LECANEMAB, MELATONIN, NICOTINAMIDE, RAPAMYCIN, SEMAGLUTIDE |
| Interactions | A2M, ABCA1, ABCA7, ABI3, ACE, ACETYLCHOLINE |
| KG Connections | 4765 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
graph TD
AMYLOID_BETA_PROTEIN["AMYLOID-BETA-PROTEIN"]
AMYLOID["AMYLOID"]
AMYLOID_BETA_PROTEIN -->|"regulates"| AMYLOID
AMYLOID_BETA_PROTEIN -->|"associated_with"| AMYLOID
AMYLOID_BETA_PROTEIN -->|"interacts_with"| AMYLOID
AMYLOID_BETA_PROTEIN -->|"activates"| AMYLOID
AMYLOID_BETA_PROTEIN -->|"co_discussed"| AMYLOID
AMYLOID_BETA_PROTEIN -->|"biomarker_for"| AMYLOID
HUNTINGTON_S_DISEASE["HUNTINGTON'S DISEASE"]
AMYLOID_BETA_PROTEIN -->|"protects_against"| HUNTINGTON_S_DISEASE
SYNA["SYNA"]
AMYLOID_BETA_PROTEIN -->|"co_discussed"| SYNA
CD2AP["CD2AP"]
AMYLOID_BETA_PROTEIN -->|"associated_with"| CD2AP
AMYLOID_BETA_PROTEIN -->|"biomarker_for"| AMYLOID
AMYLOID_BETA_PROTEIN -->|"implicated_in"| AMYLOID
AMYLOID_BETA_PROTEIN -->|"activates"| AMYLOID
style AMYLOID_BETA_PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0
style AMYLOID fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style HUNTINGTON_S_DISEASE fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style SYNA fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style CD2AP fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| entities-ampk | interacts_with | wiki | 0.00 |
| entities-ferroptosis | interacts_with | wiki | 0.00 |
| entities-glymphatic-system | interacts_with | wiki | 0.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning AMYLOID-BETA-PROTEIN in their description or question text
No additional research found