concept

WNT PATHWAY

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about WNT PATHWAY: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

24Connections

0Hypotheses

1Analyses

13Outgoing

11Incoming

0Experiments

1Debates

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💡 Concept Info

Name	WNT PATHWAY
Key Genes/Proteins	TAU, WNT3A
Related Diseases	NEUROGENESIS, TAU PHOSPHORYLATION

Pathway Diagram

graph TD
    WNT_PATHWAY[WNT PATHWAY]
    WNT_PATHWAY -->|involved_in| Tumor_Growth[Tumor Growth]
    WNT_PATHWAY -->|regulates| stem_cells[stem cells]
    WNT_PATHWAY -->|involved_in| Tumor_Invasion[Tumor Invasion]
    WNT_PATHWAY -->|causes| cancer[cancer]
    WNT_PATHWAY -->|participates in| ESCC[ESCC]
    WNT3A[WNT3A] -->|activates| WNT_PATHWAY
    GEFITINIB[GEFITINIB] -->|activates| WNT_PATHWAY
    TAU_PHOSPHORYLATION[TAU PHOSPHORYLATION] -->|regulates| WNT_PATHWAY

Outgoing (13)

Target	Relation	Type	Str
Tumor Growth	involved_in	process	0.90
stem cells	regulates	cell_type	0.90
Tumor Invasion	involved_in	process	0.85
cancer	causes	disease	0.80
ESCC	participates_in	disease	0.70
WNT3A	associated_with	gene	0.50
GEFITINIB	associated_with	drug	0.50
ASTROCYTES	associated_with	cell_type	0.50
STEM CELLS	associated_with	cell_type	0.50
NEURONS	associated_with	cell_type	0.50
TAU	associated_with	protein	0.45
HIPPOCAMPUS	associated_with	brain_region	0.45
CORTEX	associated_with	brain_region	0.45

Incoming (11)

Source	Relation	Type	Str
Glioblastoma Multiforme	associated_with	disease	0.95
WNT3A	activates	gene	0.70
GSK3β activity	regulated_by	process	0.70
GEFITINIB	activates	drug	0.65
TAU PHOSPHORYLATION	regulates	phenotype	0.65
OLIGODENDROCYTES	associated_with	cell_type	0.50
NEURAL STEM CELLS	associated_with	cell_type	0.50
NEUROGENESIS	associated_with	phenotype	0.50
ENTORHINAL CORTEX	associated_with	brain_region	0.45
TEMPORAL LOBE	associated_with	brain_region	0.45
TAU PHOSPHORYLATION	associated_with	phenotype	0.45

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (1)

Scientific analyses that reference this entity

Can CSF p-tau217 normalization serve as a reliable surrogate endpoint for determ

neurodegeneration | 2026-04-26 | 7 hypotheses Top: 0.585

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (1)

Multi-agent debates referencing this entity

Can CSF p-tau217 normalization serve as a reliable surrogate endpoint for determ

closed · Rounds: 4 · Score: 1.00 · 2026-04-26

Related Research

Hypotheses and analyses mentioning WNT PATHWAY in their description or question text

No additional research found