concept

USP9X

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about USP9X: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

37Connections

0Hypotheses

0Analyses

20Outgoing

17Incoming

0Experiments

0Debates

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💡 Concept Info

Name	USP9X
Key Genes/Proteins	AMPK, GBM, HDAC6, NLRP3
Related Diseases	glioblastoma, neurodegeneration, Neurodegenerative Diseases, neuroinflammation
Related Pathways	autophagy pathway, epigenetic regulation

Pathway Diagram

graph TD
    USP9X[USP9X]
    USP9X -->|regulates| Nlrp3_Inflammasome[Nlrp3 Inflammasome]
    USP9X -->|target for| Parkinson_S_Disease[Parkinson'S Disease]
    USP9X -->|promotes| neurogenesis[neurogenesis]
    USP9X -->|involved_in| Neurogenesis[Neurogenesis]
    USP9X -->|expressed in| neurodegeneration[neurodegeneration]
    USP9X -->|inhibits| neuroinflammation[neuroinflammation]
    USP9X -->|participates in| ubiquitin_proteasome[ubiquitin-proteasome]
    USP9X -->|activates| Parkinson_s_disease[Parkinson's disease]
    USP9X -->|participates in| pyroptosis[pyroptosis]
    TAK1[TAK1] -->|activates| USP9X
    NLRP3[NLRP3] -->|activates| USP9X
    RAPTOR[RAPTOR] -->|interacts| USP9X
    USP14[USP14] -->|implicated in| USP9X
    GBM[GBM] -->|targets| USP9X
    HDAC6[HDAC6] -->|targets| USP9X
    AMPK[AMPK] -->|activates| USP9X

Outgoing (20)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:USP9X	data_in	dataset_row	0.00
Nlrp3 Inflammasome	regulates	pathway	0.95
UBIQUITIN	associated_with	protein	0.95
Parkinson'S Disease	therapeutic_target	disease	0.90
Neurodegenerative Diseases	associated_with	disease	0.90
Neurogenesis	involved_in	process	0.85
neurogenesis	promotes	process	0.85
pyroptosis	participates_in	pathway	0.60
ubiquitin-proteasome	participates_in	pathway	0.60
glioblastoma	targets	disease	0.60
glioblastoma	associated_with	disease	0.60
glioblastoma	activates	disease	0.60
epigenetic regulation	participates_in	pathway	0.60
Parkinson's disease	activates	disease	0.60
Parkinson's disease	inhibits	disease	0.60
autophagy pathway	participates_in	pathway	0.60
neurodegeneration	expressed_in	disease	0.60
neuroinflammation	inhibits	disease	0.60
neurons	expressed_in	cell_type	0.55
microglia	expressed_in	cell_type	0.55

Incoming (17)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:USP9X	data_in	dataset_row	0.00
USP27X	associated_with	gene	0.60
USP7	associated_with	gene	0.60
GBM	targets	gene	0.60
HDAC6	targets	gene	0.60
UCHL1	associated_with	gene	0.60
HDAC6	associated_with	gene	0.60
HDAC6	regulates	gene	0.60
GBM	activates	gene	0.60
HDAC6	activates	gene	0.60
GBM	associated_with	gene	0.60
TAK1	activates	gene	0.60
NLRP3	activates	gene	0.60
AMPK	activates	gene	0.60
RAPTOR	interacts_with	gene	0.60
USP14	implicated_in	gene	0.60
USP5	implicated_in	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning USP9X in their description or question text

No additional research found