gene

SYT7

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SYT7: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

42Connections

0Hypotheses

0Analyses

36Outgoing

6Incoming

0Experiments

0Debates

Summary

SYT7 Gene

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🧬 Gene Info

Gene Symbol	SYT7
Protein Type	Gene
Function	Synaptotagmin 7 (SYT7) is a member of the synaptotagmin family of calcium-binding proteins that function as calcium sensors for neurotransmitter release.
Primary Expression	hippocampus, cerebellum, striatum, cortex, Cortex
Pathways	Synaptic Plasticity
GeneCards	SYT7
Human Protein Atlas	SYT7
Associated Diseases	neurodegeneration
Interactions	Actin, AND, Proteins, RNA, SYNCRIP
KG Connections	42 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

SYT7 Gene

gene · 638 words

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Pathway Diagram

graph TD
    SYT7["SYT7"]
    Als["Als"]
    SYT7 -->|"interacts with"| Als
    Neurodegeneration["Neurodegeneration"]
    SYT7 -->|"regulates"| Neurodegeneration
    ALS["ALS"]
    SYT7 -->|"interacts with"| ALS
    Synaptic_Plasticity["Synaptic Plasticity"]
    SYT7 -->|"interacts with"| Synaptic_Plasticity
    Purkinje["Purkinje"]
    SYT7 -->|"expressed in"| Purkinje
    Neuron["Neuron"]
    SYT7 -->|"expressed in"| Neuron
    RNA["RNA"]
    SYT7 -->|"interacts with"| RNA
    AND["AND"]
    SYT7 -->|"interacts with"| AND
    SYNCRIP["SYNCRIP"]
    SYNCRIP -->|"interacts with"| SYT7
    SYNCRIP["SYNCRIP"]
    SYNCRIP -->|"co expressed with"| SYT7
    NEURODEGENERATION["NEURODEGENERATION"]
    NEURODEGENERATION -->|"regulates"| SYT7
    Cortex["Cortex"]
    SYT7 -->|"expressed in"| Cortex
    Hippocampus["Hippocampus"]
    SYT7 -->|"expressed in"| Hippocampus
    Cerebellum["Cerebellum"]
    SYT7 -->|"expressed in"| Cerebellum
    Striatum["Striatum"]
    SYT7 -->|"expressed in"| Striatum
    SYNCRIP["SYNCRIP"]
    SYT7 -->|"interacts with"| SYNCRIP
    Cortex["Cortex"]
    SYT7 -->|"regulates"| Cortex
    Hippocampus["Hippocampus"]
    SYT7 -->|"regulates"| Hippocampus
    STRIATUM["STRIATUM"]
    SYT7 -->|"regulates"| STRIATUM
    SYNCRIP["SYNCRIP"]
    SYT7 -->|"regulates"| SYNCRIP
    Proteins["Proteins"]
    SYT7 -->|"regulates"| Proteins
    Proteins["Proteins"]
    SYT7 -->|"interacts with"| Proteins
    Cortex["Cortex"]
    SYT7 -->|"inhibits"| Cortex
    Hippocampus["Hippocampus"]
    SYT7 -->|"inhibits"| Hippocampus
    STRIATUM["STRIATUM"]
    SYT7 -->|"inhibits"| STRIATUM
    SYNCRIP["SYNCRIP"]
    SYT7 -->|"inhibits"| SYNCRIP
    CEREBRAL_CORTEX["CEREBRAL CORTEX"]
    SYT7 -->|"inhibits"| CEREBRAL_CORTEX
    Cortex["Cortex"]
    SYT7 -->|"interacts with"| Cortex
    NEURONS["NEURONS"]
    SYT7 -->|"interacts with"| NEURONS
    Neurodegeneration["Neurodegeneration"]
    Neurodegeneration -->|"regulates"| SYT7

Outgoing (36)

Target	Relation	Type	Str
ALS	interacts_with	disease	0.65
Als	interacts_with	disease	0.65
Neurodegeneration	regulates	disease	0.65
neurons	expressed_in	cell_type	0.60
neurodegeneration	regulates	disease	0.60
Synaptic Plasticity	interacts_with	pathway	0.60
Neuron	expressed_in	cell_type	0.60
Raf	expressed_in	protein	0.60
hippocampus	expressed_in	brain_region	0.60
cortex	expressed_in	brain_region	0.60
AND	interacts_with	gene	0.60
RNA	interacts_with	gene	0.60
Synaptic Plasticity	expressed_in	pathway	0.60
Actin	interacts_with	protein	0.60
cerebellum	expressed_in	brain_region	0.60
striatum	expressed_in	brain_region	0.60
Purkinje cells	expressed_in	cell_type	0.60
Purkinje	expressed_in	cell_type	0.60
Striatum	expressed_in	brain_region	0.55
Cerebellum	expressed_in	brain_region	0.55
Cortex	expressed_in	brain_region	0.55
Hippocampus	expressed_in	brain_region	0.55
Proteins	regulates	protein	0.50
Proteins	interacts_with	protein	0.50
Cortex	inhibits	brain_region	0.50
Hippocampus	inhibits	entity	0.50
STRIATUM	inhibits	concept	0.50
CEREBRAL CORTEX	inhibits	concept	0.50
Cortex	interacts_with	brain_region	0.50
NEURONS	interacts_with	concept	0.50
SYNCRIP	interacts_with	concept	0.50
SYNCRIP	regulates	concept	0.50
Cortex	regulates	brain_region	0.50
SYNCRIP	inhibits	concept	0.50
Hippocampus	regulates	entity	0.50
STRIATUM	regulates	concept	0.50

Incoming (6)

Source	Relation	Type	Str
NEURODEGENERATION	regulates	gene	0.60
SYNCRIP	interacts_with	protein	0.60
SYNCRIP	regulates	gene	0.60
SYNCRIP	expressed_in	gene	0.60
RNA	interacts_with	gene	0.60
Neurodegeneration	regulates	disease	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning SYT7 in their description or question text

No additional research found