gene

STX1A

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about STX1A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

16Connections

0Hypotheses

0Analyses

13Outgoing

3Incoming

0Experiments

0Debates

Summary

Page for STX1A Gene - Syntaxin-1A

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🧬 Gene Info

Gene Symbol	STX1A
Aliases	Page for STX1A Gene
Chromosome	7q11.23
Function	Synaptic vesicle fusion, SNARE complex formation
Primary Expression	the central nervous system and has been implicated in various neurological disorders
Molecular Weight	35 kDa
Amino Acids	288 aa
GeneCards	STX1A
Human Protein Atlas	STX1A
SNARE complex formation	Partners with SNAP-25 and synaptobrevin for vesicle fusion
Neurotransmitter release	Essential for Ca2+-triggered synaptic exocytosis
Synaptic plasticity	Regulates short-term synaptic plasticity
Disease associations	Alzheimer's disease, epilepsy, autism, schizophrenia
Associated Diseases	Alzheimer's disease, epilepsy, autism, schizophrenia
Interactions	DEPRESSION
KG Connections	16 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

STX1A Gene - Syntaxin-1A

gene · 813 words

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Pathway Diagram

graph TD
    STX1A["STX1A"]
    STX1A -->|"inhibits"| Depression["Depression"]
    STX1A -->|"inhibits"| Neuroinflammation["Neuroinflammation"]
    STX1A -->|"expressed in"| NLRP3["NLRP3"]
    STX1A -->|"expressed in"| BDNF["BDNF"]
    STX1A -->|"expressed in"| VAMP2["VAMP2"]
    STX1A -->|"expressed in"| PSD95["PSD95"]
    STX1A -->|"expressed in"| BCL_2["BCL-2"]
    STX1A -->|"expressed in"| BAX["BAX"]
    DEPRESSION["DEPRESSION"] -->|"inhibits"| STX1A

Outgoing (13)

Target	Relation	Type	Str
Neuroinflammation	inhibits	disease	0.65
Depression	inhibits	disease	0.65
VAMP2	expressed_in	gene	0.60
PSD95	expressed_in	gene	0.60
BAX	expressed_in	gene	0.60
SNAP25	expressed_in	gene	0.60
GAP43	expressed_in	gene	0.60
TRKB	expressed_in	gene	0.60
BCL-2	expressed_in	gene	0.60
Neuron	inhibits	cell_type	0.60
BDNF	expressed_in	gene	0.60
NLRP3	expressed_in	gene	0.60
STX4	regulates	gene	0.55

Incoming (3)

Source	Relation	Type	Str
DEPRESSION	inhibits	gene	0.60
SNARE	regulates	gene	0.55
STX17	regulates	gene	0.55

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning STX1A in their description or question text

No additional research found