gene 813 words KG: STX1A
Contents

STX1A Gene - Syntaxin-1A

🧬 Gene Info
Gene SymbolSTX1A
AliasesPage for STX1A Gene
Chromosome7q11.23
FunctionSynaptic vesicle fusion, SNARE complex formation
Primary Expressionthe central nervous system and has been implicated in various neurological disorders
Molecular Weight35 kDa
Amino Acids288 aa
GeneCardsSTX1A
Human Protein AtlasSTX1A
SNARE complex formationPartners with SNAP-25 and synaptobrevin for vesicle fusion
Neurotransmitter releaseEssential for Ca2+-triggered synaptic exocytosis
Synaptic plasticityRegulates short-term synaptic plasticity
Disease associationsAlzheimer's disease, epilepsy, autism, schizophrenia
Associated DiseasesAlzheimer's disease, epilepsy, autism, schizophrenia
InteractionsDEPRESSION
KG Connections16 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (3)

CYP46A1 Overexpression Gene Therapy
Score: 0.73
Autophagosome Maturation Checkpoint Control
Score: 0.71
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69

Related Analyses (4)

Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (12)

SNAP-25
biomarker · KG edge: expressed_in
NeuRon Therapeutics
company · KG edge: inhibits
Neuroinflammation PET Imaging in CBS/PSP
diagnostic · KG edge: inhibits
Neurodegeneration
disease · KG edge: implicated_in
BAX Gene
gene · KG edge: expressed_in

Knowledge Graph (12 edges)

STX1A expressed_in NLRP3
STX1A expressed_in BDNF
STX1A expressed_in VAMP2
STX1A expressed_in PSD95
STX1A expressed_in BAX
STX1A expressed_in SNAP25
STX1A expressed_in GAP43
STX1A expressed_in TRKB
STX17 regulates STX1A
STX1A regulates STX4

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