Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RPS23: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | RPS23 |
| Full Name | Ribosomal Protein S23 |
| Chromosome | 5q14.1 |
| Function | encodes a ribosomal protein that is a fundamental component of the small (40S) ribosomal subunit. |
| Subcellular Localization | - Cell body (soma) |
| Molecular Weight | 16.6 kDa |
| Amino Acids | 143 aa |
| UniProt ID | P62266 |
| NCBI Gene ID | 6209 |
| Ensembl ID | ENSG00000130712 |
| GeneCards | RPS23 |
| Human Protein Atlas | RPS23 |
| rRNA binding domain | Interacts with 18S rRNA |
| mRNA channel interface | Positions mRNA for translation |
| Initiation factor binding sites | Interacts with eIF1 and eIF3 |
| Associated Diseases | Als, Alzheimer |
| KG Connections | 17 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
flowchart TD
N0["RPS23"]
N1["Alzheimer"]
N0 -->|"associated with"| N1
N2["Als"]
N0 -->|"associated with"| N2
N3["GFAP"]
N0 -->|"associated with"| N3
N4["AMYLOID"]
N0 -->|"associated with"| N4
N5["MYT1L"]
N0 -->|"associated with"| N5
N6["APP"]
N0 -->|"associated with"| N6
N7["VGF"]
N0 -->|"associated with"| N7
N8["Microglia"]
N0 -->|"associated with"| N8
N9["APOE"]
N9 -->|"associated with"| N0
N10["PIN1"]
N10 -->|"associated with"| N0
N11["RPL24"]
N11 -->|"associated with"| N0
N12["ALZHEIMER"]
N12 -->|"associated with"| N0
N13["HSPB1"]
N13 -->|"associated with"| N0
N14["MITOCHONDRIA"]
N14 -->|"associated with"| N0
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class N1 disease
class N2 disease
class N3 gene
class N4 gene
class N5 gene
class N6 gene
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class N13 gene
class N14 geneHypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning RPS23 in their description or question text
No additional research found