gene

RALB

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about RALB: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

16Connections

0Hypotheses

0Analyses

6Outgoing

10Incoming

0Experiments

0Debates

Summary

RALB is a gene implicated in neurodegeneration research. Key relationships include: associated with, expressed in, implicated in. Associated with Als, Ms. Connected to 17 entities in the SciDEX knowledge graph.

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🧬 Gene Info

Gene Symbol	RALB
Aliases	Page for RALB Gene, Page for RALB Protein
Chromosome	2p22.3
Function	is an important component in the neurobiology of neurodegenerative diseases.
Primary Expression	Brain (cerebral cortex, hippocampus, cerebellum), Lung, Liver, Kidney
Molecular Weight	23 kDa
Amino Acids	206 aa
UniProt ID	P11234
NCBI Gene ID	5878
Ensembl ID	ENSG00000128045
OMIM	179897
GeneCards	RALB
Human Protein Atlas	RALB
Associated Diseases	Als, Ms
KG Connections	16 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: RALB — AlphaFold P11234 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

RALB Gene - RAS-Related Protein Ral-B

gene · 1038 words

→

RALB Protein - RAS-Related Protein Ral-B

protein · 1126 words

→

Pathway Diagram

graph TD
    RALB["RALB"]
    Als{"Als"}
    RALB -->|"associated with"| Als
    Ms{"Ms"}
    RALB -->|"associated with"| Ms
    AUTOPHAGY_RELATED_GENES["AUTOPHAGY-RELATED GENES"]
    RALB -->|"associated with"| AUTOPHAGY_RELATED_GENES
    GNAI3["GNAI3"]
    RALB -->|"expressed in"| GNAI3
    WIPI1["WIPI1"]
    RALB -->|"expressed in"| WIPI1
    Autophagy(["Autophagy"])
    RALB -->|"associated with"| Autophagy
    neurodegeneration["neurodegeneration"]
    RALB -->|"implicated in"| neurodegeneration
    MIRNAS["MIRNAS"]
    MIRNAS -->|"associated with"| RALB
    C9ORF72["C9ORF72"]
    C9ORF72 -->|"expressed in"| RALB
    CD8["CD8"]
    CD8 -->|"associated with"| RALB
    LRRK2["LRRK2"]
    LRRK2 -->|"expressed in"| RALB
    IMMUNE_INFILTRATION["IMMUNE INFILTRATION"]
    IMMUNE_INFILTRATION -->|"associated with"| RALB
    MICRORNAS["MICRORNAS"]
    MICRORNAS -->|"associated with"| RALB
    AUTOPHAGY["AUTOPHAGY"]
    AUTOPHAGY -->|"associated with"| RALB
    GBA["GBA"]
    GBA -->|"expressed in"| RALB
    WDFY3["WDFY3"]
    WDFY3 -->|"expressed in"| RALB
    PIK3CB["PIK3CB"]
    PIK3CB -->|"expressed in"| RALB
    style RALB fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (6)

Target	Relation	Type	Str
Als	associated_with	disease	0.65
Ms	associated_with	disease	0.65
AUTOPHAGY-RELATED GENES	associated_with	gene	0.60
Autophagy	associated_with	pathway	0.60
GNAI3	expressed_in	gene	0.60
WIPI1	expressed_in	gene	0.60

Incoming (10)

Source	Relation	Type	Str
MIRNAS	associated_with	gene	0.60
IMMUNE INFILTRATION	associated_with	gene	0.60
MICRORNAS	associated_with	gene	0.60
AUTOPHAGY	associated_with	gene	0.60
C9ORF72	expressed_in	gene	0.60
CD8	associated_with	gene	0.60
LRRK2	expressed_in	gene	0.60
GBA	expressed_in	gene	0.60
WDFY3	expressed_in	gene	0.60
PIK3CB	expressed_in	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning RALB in their description or question text

No additional research found