concept

PHIP

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PHIP: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

47Connections

0Hypotheses

0Analyses

36Outgoing

11Incoming

0Experiments

0Debates

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💡 Concept Info

Name	PHIP
Key Genes/Proteins	Akt, AKT, AND, ANXA2, ASTROCYTE, FN1
Related Diseases	Als, ALS, glioblastoma
Related Pathways	Angiogenesis, Epigenetic

Pathway Diagram

graph TD
    PHIP["PHIP"]
    PHIP -->|"modulates"| Glioblastoma_Invasion["Glioblastoma Invasion"]
    PHIP -->|"regulates"| Tumor["Tumor"]
    PHIP -->|"activates"| ALS["ALS"]
    PHIP -->|"activates"| Glioblastoma["Glioblastoma"]
    PHIP -->|"target for"| Als["Als"]
    PHIP -->|"regulates"| ANXA2["ANXA2"]
    PHIP -->|"regulates"| AND["AND"]
    GENES["GENES"] -->|"regulates"| PHIP
    GBM["GBM"] -->|"regulates"| PHIP
    AKT["AKT"] -->|"activates"| PHIP
    ASTROCYTE["ASTROCYTE"] -->|"activates"| PHIP
    FN1["FN1"] -->|"regulates"| PHIP
    MTOR["MTOR"] -->|"activates"| PHIP
    ANXA2 -->|"regulates"| PHIP
    GLUT3["GLUT3"] -->|"regulates"| PHIP

Outgoing (36)

Target	Relation	Type	Str
Glioblastoma Invasion	modulates	phenotype	0.80
ALS	activates	disease	0.65
Tumor	regulates	disease	0.65
Glioblastoma	activates	disease	0.65
Als	therapeutic_target	disease	0.65
Glioblastoma	therapeutic_target	disease	0.65
Immune Response	therapeutic_target	pathway	0.60
Mtor	therapeutic_target	pathway	0.60
Pi3K/Akt	therapeutic_target	pathway	0.60
Stem Cell	therapeutic_target	cell_type	0.60
GLIOBLASTOMA	therapeutic_target	gene	0.60
Astrocyte	therapeutic_target	cell_type	0.60
Epigenetic	therapeutic_target	pathway	0.60
glioblastoma	regulates	disease	0.60
oxidative stress response	participates_in	pathway	0.60
T cells	expressed_in	cell_type	0.60
GBM	regulates	gene	0.60
Radial Glia	therapeutic_target	cell_type	0.60
Akt	therapeutic_target	protein	0.60
Pi3K	therapeutic_target	protein	0.60
MTOR	activates	gene	0.60
FN1	regulates	gene	0.60
GBP2	regulates	gene	0.60
GLIOBLASTOMA	activates	gene	0.60
PI3K	activates	gene	0.60
Epigenetic	activates	pathway	0.60
AND	regulates	gene	0.60
GLUT3	regulates	gene	0.60
ANXA2	regulates	gene	0.60
Immune Response	activates	pathway	0.60
Mtor	activates	pathway	0.60
Pi3K/Akt	activates	pathway	0.60
Angiogenesis	activates	pathway	0.60
Stem Cell	expressed_in	cell_type	0.55
Neural Stem Cell	expressed_in	cell_type	0.55
Astrocyte	expressed_in	cell_type	0.55

Incoming (11)

Source	Relation	Type	Str
GENES	regulates	gene	0.60
GBM	regulates	gene	0.60
AKT	activates	gene	0.60
ASTROCYTE	activates	gene	0.60
GLIOBLASTOMA	therapeutic_target	gene	0.60
GBP2	regulates	gene	0.60
FN1	regulates	gene	0.60
MTOR	activates	gene	0.60
ANXA2	regulates	gene	0.60
GLUT3	regulates	gene	0.60
PI3K	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning PHIP in their description or question text

No additional research found