Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about MEF2 TARGET GENES: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | MEF2 TARGET GENES |
| Key Genes/Proteins | AKT, AND, GENES, HDAC, HDAC4, HDAC7 |
| Related Diseases | ALS, Tumor |
| Related Pathways | Pi3K/Akt |
graph TD
MEF2_TARGET_GENES["MEF2 TARGET GENES"]
MEF2_TARGET_GENES -->|"inhibits"| PI3K["PI3K"]
MEF2_TARGET_GENES -->|"inhibits"| Pi3K_Akt["Pi3K/Akt"]
MEF2_TARGET_GENES -->|"inhibits"| HDAC["HDAC"]
MEF2_TARGET_GENES -->|"inhibits"| AND["AND"]
MEF2_TARGET_GENES -->|"inhibits"| GENES["GENES"]
HDAC4["HDAC4"] -->|"downregulates"| MEF2_TARGET_GENES
PI3K -->|"regulates"| MEF2_TARGET_GENES
GENES -->|"inhibits"| MEF2_TARGET_GENES
AKT["AKT"] -->|"inhibits"| MEF2_TARGET_GENES
HDAC -->|"inhibits"| MEF2_TARGET_GENES
AND -->|"inhibits"| MEF2_TARGET_GENES| Source | Relation | Type | Str |
|---|---|---|---|
| HDAC4 | downregulates | protein | 0.95 |
| 19109909 | have diverse functions at | paper | 0.90 |
| 19109909 | are mutated in | paper | 0.90 |
| HDAC4 | downregulates | protein | 0.90 |
| HDAC7 | associated_with | gene | 0.60 |
| PI3K | inhibits | gene | 0.60 |
| HDAC4 | associated_with | gene | 0.60 |
| GENES | inhibits | gene | 0.60 |
| AKT | inhibits | gene | 0.60 |
| HDAC | inhibits | gene | 0.60 |
| PTEN | associated_with | gene | 0.60 |
| AND | inhibits | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning MEF2 TARGET GENES in their description or question text
No additional research found