gene

IL7

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about IL7: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

16Connections

0Hypotheses

0Analyses

14Outgoing

2Incoming

0Experiments

0Debates

Summary

IL7 is a gene implicated in neurodegeneration research. Key relationships include: associated with, implicated in. Associated with Fibrosis, Inflammation, Ms. Connected to 17 entities in the SciDEX knowledge graph.

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🧬 Gene Info

Gene Symbol	IL7
Chromosome	8q21.11
Protein Type	Cytokine
Function	IL-7 has essential functions in immune development and homeostasis:
Primary Expression	various cell types and influences neuroinflammation, neural precursor cell function, and has been implicated in neurodegenerative and psychiatric diso
Molecular Weight	20 kDa
Pathways	PI3K, MAPK
NCBI Gene ID	3564
GeneCards	IL7
Human Protein Atlas	IL7
Associated Diseases	Fibrosis, Inflammation, Ms
KG Connections	16 knowledge graph edges
Databases	GeneCards UniProt HPA STRING

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

IL7 Gene

gene · 579 words

→

IL7R Gene - Interleukin-7 Receptor Alpha Chain

gene · 754 words

→

Pathway Diagram

graph TD
    IL7["IL7"]
    Fibrosis{"Fibrosis"}
    IL7 -->|"associated with"| Fibrosis
    Ms{"Ms"}
    IL7 -->|"associated with"| Ms
    Inflammation{"Inflammation"}
    IL7 -->|"associated with"| Inflammation
    PI3K["PI3K"]
    IL7 -->|"associated with"| PI3K
    IL18["IL18"]
    IL7 -->|"associated with"| IL18
    IL7R["IL7R"]
    IL7 -->|"associated with"| IL7R
    CCL5["CCL5"]
    IL7 -->|"associated with"| CCL5
    AKT["AKT"]
    IL7 -->|"associated with"| AKT
    INFLAMMATION["INFLAMMATION"]
    IL7 -->|"associated with"| INFLAMMATION
    IMMUNE_INFILTRATION["IMMUNE INFILTRATION"]
    IL7 -->|"associated with"| IMMUNE_INFILTRATION
    CXCL10["CXCL10"]
    IL7 -->|"associated with"| CXCL10
    Toll_Like_Receptor(["Toll-Like Receptor"])
    IL7 -->|"associated with"| Toll_Like_Receptor
    CXCL8["CXCL8"]
    CXCL8 -->|"associated with"| IL7
    CCL4["CCL4"]
    CCL4 -->|"associated with"| IL7
    style IL7 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (14)

Target	Relation	Type	Str
Fibrosis	associated_with	disease	0.65
Ms	associated_with	disease	0.65
Inflammation	associated_with	disease	0.65
Akt	associated_with	pathway	0.60
INFLAMMATION	associated_with	gene	0.60
Pi3K	associated_with	pathway	0.60
IMMUNE INFILTRATION	associated_with	gene	0.60
Toll-Like Receptor	associated_with	pathway	0.60
PI3K	associated_with	gene	0.60
IL18	associated_with	gene	0.60
IL7R	associated_with	gene	0.60
CCL5	associated_with	gene	0.60
AKT	associated_with	gene	0.60
CXCL10	associated_with	gene	0.60

Incoming (2)

Source	Relation	Type	Str
CXCL8	associated_with	gene	0.60
CCL4	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning IL7 in their description or question text

No additional research found