Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CCNA1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | CCNA1 |
| Key Genes/Proteins | AND, App, ARNT, BMAL1, CDK1, CLOCK |
| Related Diseases | Als, ALS |
| Related Pathways | Angiogenesis, Cell Cycle |
graph TD
CCNA1["CCNA1"]
CCNA1 -->|"regulates"| Als["Als"]
CCNA1 -->|"regulates"| ALS["ALS"]
CCNA1 -->|"regulates"| CLOCK["CLOCK"]
CCNA1 -->|"regulates"| Angiogenesis["Angiogenesis"]
CCNA1 -->|"activates"| BMAL1["BMAL1"]
CCNA1 -->|"activates"| CDK1["CDK1"]
CCNA1 -->|"regulates"| ARNT["ARNT"]
CCNA1 -->|"regulates"| Cell_Cycle["Cell Cycle"]
BMAL1 -->|"upregulates"| CCNA1
CDK1 -->|"activates"| CCNA1
ARNT -->|"regulates"| CCNA1
GENES["GENES"] -->|"activates"| CCNA1
CLOCK -->|"regulates"| CCNA1| Target | Relation | Type | Str |
|---|---|---|---|
| Als | regulates | disease | 0.65 |
| ALS | regulates | disease | 0.65 |
| GENES | activates | gene | 0.60 |
| Angiogenesis | regulates | pathway | 0.60 |
| BMAL1 | activates | gene | 0.60 |
| CDK1 | activates | gene | 0.60 |
| ARNT | regulates | gene | 0.60 |
| RNA | activates | gene | 0.60 |
| AND | activates | gene | 0.60 |
| Endothelial | regulates | cell_type | 0.60 |
| CLOCK | regulates | gene | 0.60 |
| CLOCK GENES | regulates | gene | 0.60 |
| Rb | regulates | protein | 0.60 |
| App | activates | protein | 0.60 |
| Cell Cycle | regulates | pathway | 0.60 |
| Endothelial Cell | expressed_in | cell_type | 0.55 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning CCNA1 in their description or question text
No additional research found