Closed-loop transcranial focused ultrasound to restore hippocampal gamma oscillations via direct PV interneuron recruitment in Alzheimer's disease
h-var-6612521a02
## Mechanistic Overview
Closed-loop transcranial focused ultrasound to restore hippocampal gamma oscillations via direct PV interneuron recruitment in Alzheimer's disease starts from the claim that modulating PVALB within the disease context of Alzheimer's disease can redirect a disease-relevant process. The original description reads: "**Background and Rationale** Alzheimer's disease (AD) manifes
Elo ratings (across arenas)
| Arena | Rating | RD | W-L-D | N |
|---|---|---|---|---|
| alzheimers | 2282 | ±86 | 45-3-0 | 48 |
| global | 2112 | ±149 | 11-0-0 | 11 |
| loop:loop-74f20cb27aad | 1583 | ±292 | 0-0-1 | 1 |
Ancestry (oldest → this)
mutate · gen 1
parent: h-bdbd2120
mutate · gen 2
parent: h-var-d749cd28cb
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