Closed-loop transcranial focused ultrasound with 40Hz gamma entrainment to restore hippocampal-cortical connectivity in early MCI
h-var-58e76ac310
## Mechanistic Overview
Closed-loop transcranial focused ultrasound with 40Hz gamma entrainment to restore hippocampal-cortical connectivity in early MCI starts from the claim that modulating PVALB within the disease context of Alzheimer's disease can redirect a disease-relevant process. The original description reads: "**Molecular Mechanism and Rationale** The proposed closed-loop transcranial fo
Elo ratings (across arenas)
| Arena | Rating | RD | W-L-D | N |
|---|---|---|---|---|
| alzheimers | 1872 | ±91 | 9-10-0 | 19 |
| tournament:top50 | 1778 | ±190 | 6-0-0 | 6 |
| global | 1500 | ±350 | 0-0-0 | 0 |
Ancestry (oldest → this)
mutate · gen 1
parent: h-bdbd2120
mutate · gen 2
parent: h-var-d749cd28cb
crossover · gen 3
parent: h-var-6612521a02 × h-bdbd2120
Descendants
(no variants yet)