| Gene Symbol | SOD1 |
| Full Name | Targeting Therapies |
| Chromosome | 21q22.11 |
| Protein Type | Enzyme |
| Function | is a copper/zinc-dependent enzyme that catalyzes the dismutation of superoxide radical (O₂⁻) into molecular oxygen (O₂) and hydrogen peroxide (H₂O₂). |
| Primary Expression | Motor cortex, Spinal cord, Widespread throughout CNS |
| Molecular Weight | 16 kDa |
| Amino Acids | 154 aa |
| Pathways | Amyloid, Apoptosis, Autophagy, Epigenetic, Er Stress |
| Ensembl ID | ENSG00000142168 |
| GeneCards | SOD1 |
| Human Protein Atlas | SOD1 |
| Associated Diseases | AD, Aging, Als, Alzheimer |
| Known Drugs/Compounds | Amyloid-Beta Oligomers, antisense oligonucleotides, Antisense Oligonucleotides, ARIMOCLOMOL, CISPLATIN, curcumin |
| Interactions | ACTB, ACTG1, AD, AGING, AKT, AKT1 |
| KG Connections | 2192 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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