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therapeutic 683 words KG: GABA
Contents

Baclofen

💊 Therapeutic Info
NameGABA
Key Genes/ProteinsABCA7, ACTB, Actin, ADRA2B, Akt, AKT
Related Diseasesacetylcholine, Aging, AGING, Als, ALS
Linked Hypotheses12 hypotheses

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🌐 Cross-references

Wikipedia

Related Hypotheses (4)

APOE-Dependent Autophagy Restoration
Score: 0.88Circadian-Synchronized Proteostasis Enhancement
Score: 0.74The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction
Score: 0.65TFEB-PGC1α Mitochondrial-Lysosomal Decoupling
Score: 0.62

Related Analyses (2)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archivedBlood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived

Related Experiments (6)

iPSC-NPC effects on astrocytes in vitro ICH model
exploratory · completed · Score: 0.90Trehalose-induced lysosomal changes and TFEB activation
exploratory · proposed · Score: 0.90Trehalose-induced lysosomal membrane permeabilization and TF
exploratory · proposed · Score: 0.90Functional validation of trehalose effects on misfolded prot
exploratory · proposed · Score: 0.85P2RY12-MTOR pathway interaction in VSMCs
exploratory · proposed · Score: 0.85

Knowledge Graph (12 edges)

GABA associated_with MTOR
GABA associated_with TFEB
AKT associated_with GABA
BACE1 associated_with GABA
TAU associated_with GABA
GABA associated_with neuroinflammation
GABA associated_with serotonin
GABA associated_with GABAergic neurons
GABA interacts_with GABARAP
FLCN interacts_with GABA

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