protein 586 words KG: VEGFAPROTEIN
Contents

VEGFA Protein - Vascular Endothelial Growth Factor A

🔬 Protein Info
Gene SymbolVEGFA
Full NameVascular Endothelial Growth Factor A
AliasesPage for VEGFA Protein
FunctionVEGF exerts its effects by binding to receptor tyrosine kinases (VEGFR-1/Flt-1 and VEGFR-2/KDR/Flk-1) on endothelial cells and other cell types.
Subcellular Localization</th><td>Secreted, extracellular</td></tr>
Molecular Weight24 kDa
PathwaysAkt, Autophagy, Mapk, Oxidative Stress, Pi3K
Ensembl IDENSG00000112715
GeneCardsVEGFA
Human Protein AtlasVEGFA
Associated DiseasesAD, Aging, ALI, Als, Alzheimer, AMI
Known Drugs/Compoundsquercetin
InteractionsACTB, AGGF1, AKT, AKT1, ALS, ALZHEIMER
SciDEX HypothesesSpinal Vascular Unit Breakdown as Universal Driver
KG Connections964 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

UniProtWikipedia

Related Hypotheses (8)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.38
Circadian Rhythm Entrainment of Reactive Astrocytes
Score: 0.72
Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73
Retinal Vascular Microcirculation Rescue
Score: 0.72
Endothelial Glycocalyx Regeneration via Syndecan-1 Upregulat
Score: 0.71
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (10)

What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived

Related Experiments (1)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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