gene

aggf1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about aggf1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

12Connections

0Hypotheses

0Analyses

11Outgoing

1Incoming

0Experiments

0Debates

No summary available yet.

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🧬 Gene Info

Gene Symbol	AGGF1
Aliases	Page for AGGF1 Gene
Chromosome	5q13.2
Function	AGGF1 has several important molecular functions
Primary Expression	Endothelial Cells, Brain, Heart, Lung
UniProt ID	Q9Y5K8
NCBI Gene ID	55109
Ensembl ID	ENSG00000100985
OMIM	609589
GeneCards	AGGF1
Human Protein Atlas	AGGF1
Databases	GeneCards HPA STRING

🔮 Predicted Structure: aggf1 — AlphaFold Q9Y5K8 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

AGGF1 Gene - Angiogenic Factor

gene · 1339 words

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Pathway Diagram

flowchart TD
    N0["AGGF1"]
    N1["VEGFA"]
    N0 -->|"activates"| N1
    N2["FLT4"]
    N0 -->|"upregulates"| N2
    N3["EPHB4"]
    N0 -->|"upregulates"| N3
    N4["DAB2"]
    N0 -->|"upregulates"| N4
    N5["AKT"]
    N0 -->|"activates"| N5
    N6["TNFSF12"]
    N0 -->|"upregulates"| N6
    N7["ITGA7"]
    N0 -->|"binds"| N7
    N8["TP53"]
    N0 -->|"stabilizes"| N8
    N9["GATA1"]
    N9 -->|"upregulates"| N0
    N10["HIF1A"]
    N10 -->|"upregulates"| N0
    N11["PERK"]
    N0 -.->|"inhibits"| N11
    N12["MCL1"]
    N0 -->|"upregulates"| N12
    N13["neurodegeneration"]
    N0 -->|"implicated in"| N13

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    classDef therapeutic fill:#1a2a2a,stroke:#26a69a,color:#e0e0e0
    class N1 gene
    class N2 gene
    class N3 gene
    class N4 gene
    class N5 gene
    class N6 gene
    class N7 gene
    class N8 gene
    class N11 gene
    class N12 gene

Outgoing (11)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:AGGF1	data_in	dataset_row	0.00
VEGFA	activates	gene	0.80
EPHB4	upregulates	gene	0.80
DAB2	upregulates	gene	0.80
AKT	activates	gene	0.80
TNFSF12	upregulates	gene	0.80
ITGA7	binds	gene	0.80
TP53	stabilizes	gene	0.80
FLT4	upregulates	gene	0.80
MCL1	upregulates	gene	0.70
PERK	inhibits	gene	0.70

Incoming (1)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:AGGF1	data_in	dataset_row	0.00

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning aggf1 in their description or question text

No additional research found