| Gene Symbol | TRKC |
| Chromosome | 15q25.3 |
| Protein Type | Receptor |
| Function | TrkC is the primary receptor for neurotrophin-3 (NT-3) |
| Primary Expression | proprioceptive neurons, motor neurons, and certain populations of hippocampal and cortical neurons |
| Subcellular Localization | </strong></td><td>Plasma membrane, endosomes</td></tr> |
| Molecular Weight | 145 kDa |
| Amino Acids | 821 aa |
| Exons | 26 |
| Pathways | signaling: - Supports sensory neuron survival, PI3K, MAPK |
| GeneCards | TRKC |
| Human Protein Atlas | TRKC |
| Leucine-rich repeats (LRRs) | Mediate initial ligand binding specificity |
| Cysteine-rich domains | Stabilize ligand-receptor interactions |
| Ig-like C2-type domains | Provide additional ligand interaction surfaces |
| Associated Diseases | Alzheimer |
| Interactions | ALZHEIMER, AMYLOID, Amyloid Beta, AND, Aβ, Bdnf |
| KG Connections | 71 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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