protein 1,058 words KG: SREBP1PROTEIN
Contents

SREBP1 Protein (Sterol Regulatory Element-Binding Protein 1)

🔬 Protein Info
Gene SymbolSREBP1
AliasesSterol Regulatory Element-Binding Protein 1
FunctionRegulatory Element-Binding Protein 1)
Molecular Weight125 kDa
Amino Acids480 aa
PathwaysFatty Acid Synthesis, Cholesterol Synthesis, Lipid Metabolism, Mtor, Cholesterol
GeneCardsSREBP1
Human Protein AtlasSREBP1
Associated DiseasesAls, cancer, Carcinoma, ferroptosis, Hepatocellular Carcinoma, Neurodegeneration
Known Drugs/CompoundsNobiletin, NOBILETIN, rapamycin
InteractionsACLY, AHR, AKT, AMPK, AMYLOID, AND
KG Connections214 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (15)

Cholesterol-CRISPR Convergence Therapy for Neurodegeneration
Score: 0.62
Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.72
Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.91
APOE-Dependent Autophagy Restoration
Score: 0.85
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79

Related Analyses (7)

Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · completed
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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