protein 1,030 words KG: SOD2PROTEIN
Contents

SOD2 Protein

🔬 Protein Info
Gene SymbolSOD2
Full NameSuperoxide Dismutase 2, Mitochondrial
AliasesSOD2PROTEIN
Chromosome6q25.3
FunctionSOD2 provides essential mitochondrial antioxidant defense
Molecular Weight22.3 kDa
Amino Acids222 aa
Exons5
PathwaysAkt, Apoptosis, Mapk, Mitochondrial Function, Mtor
NCBI Gene ID6648
Ensembl IDENSG00000112096
OMIM147460
GeneCardsSOD2
Human Protein AtlasSOD2
Histidine 26, 74, 157Direct metal coordination
Associated DiseasesAging, Als, Alzheimer, Amyotrophic Lateral Sclerosis, Cancer
Known Drugs/Compoundsberberine, BERBERINE, Lactiplantibacillus plantarum FRT4, resveratrol, RESVERATROL
InteractionsACHE, AD, AGING, AKT, ALZHEIMER, ALZHEIMER'S DISEASE
KG Connections820 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

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Related Hypotheses (12)

Transcriptional Autophagy-Lysosome Coupling
Score: 0.88
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.73
Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.70
Mitochondrial Transfer Pathway Enhancement
Score: 0.70
RAB27A-dependent extracellular vesicle engineering for mitoc
Score: 0.67
Mitochondrial Calcium Buffering Enhancement via MCU Modulati
Score: 0.65
FOXO3-Longevity Pathway Epigenetic Reprogramming
Score: 0.63
Circadian-Gated Maresin Biosynthesis Amplification
Score: 0.56
SIRT3-Mediated Mitochondrial Deacetylation Failure with PINK
Score: 0.74
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (11)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Epigenetic clocks and biological aging in neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived

See Also (15)

Exosomal Biomarkers in Neurodegeneration
biomarker · Pages share 8 hypotheses
Exosomal miR-155 in Neurodegeneration
biomarker · Pages share 8 hypotheses
IL-6 (Interleukin-6) in Neurodegeneration
biomarker · Pages share 8 hypotheses
Liquid Biopsy in Neurodegeneration
biomarker · Pages share 8 hypotheses
Metabolomic Biomarkers in Neurodegeneration
biomarker · Pages share 8 hypotheses

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