| Gene Symbol | PALB2 |
| Full Name | Partner And Localizer of BRCA2 |
| Aliases | PALB2PROTEIN |
| Chromosome | 16p12.2 |
| Function | encodes a critical DNA repair protein that serves as a central hub in the Fanconi anemia pathway and homologous recombination repair. |
| Subcellular Localization | </b></td><td>Nucleus, chromatin</td></tr> [@wang2017] |
| Molecular Weight | 130 kDa |
| Amino Acids | 1186 aa |
| Ensembl ID | ENSG00000083093 |
| GeneCards | PALB2 |
| Human Protein Atlas | PALB2 |
| Fork regression | PALB2 helps regress stalled replication forks |
| Fork remodeling | Facilitates template switching during repair |
| nucleases protection | Prevents excessive nucleolytic degradation of stalled forks |
| Associated Diseases | Cancer |
| Interactions | BRCA1, DNA, RAD18, UBIQUITIN |
| KG Connections | 56 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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