| Gene Symbol | NT5E |
| Full Name | Ecto-5'-Nucleotidase |
| Chromosome | 6q14.3 |
| Protein Type | Enzyme |
| Function | CD73 is a glycosylphosphatidylinositol (GPI)-anchored cell surface enzyme that hydrolyzes extracellular nucleotides to adenosine |
| Primary Expression | the central nervous system (CNS), where it modulates synaptic transmission, neuroinflammation, and blood-brain barrier (BBB) function |
| Subcellular Localization | ** | Cell surface (GPI-anchored), cytoplasm | |
| Molecular Weight | 70 kDa |
| Amino Acids | 320 aa |
| Pathways | Lipid Metabolism |
| UniProt ID | P21589 |
| NCBI Gene ID | 4904 |
| Ensembl ID | ENSG00000135318 |
| OMIM | 602872 |
| GeneCards | NT5E |
| Human Protein Atlas | NT5E |
| Associated Diseases | ALS, Alzheimer, dementia |
| KG Connections | 37 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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