protein 508 words KG: MAX
Contents

MAX Protein (MAX)

🔬 Protein Info
Gene SymbolMAX
Full NameMYC-associated factor X
Chromosome14q23.3
Protein FamilybHLH-LZ Transcription Factor Family
Protein TypeTranscription Factor
FunctionMYC-MAX heterodimers activate target genes
Subcellular LocalizationNuclear
Molecular Weight18 kDa
Amino Acids160 aa
PathwaysTgf-Β
UniProt IDP61275
GeneCardsMAX
Human Protein AtlasMAX
Associated DiseasesAging, Als, Autoimmune, Cancer, Ms
InteractionsAND, App, AQP4, AQUAPORIN-4, ASTROCYTE, CANCER
KG Connections215 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (9)

SASP-Driven Aquaporin-4 Dysregulation
Score: 0.78
PARP1 Inhibition Therapy
Score: 0.74
Aquaporin-4 Polarization Rescue
Score: 0.73
Mitochondrial Transfer Pathway Enhancement
Score: 0.70
Palmitoylation-Targeted BACE1 Trafficking Disruptors
Score: 0.69

Related Analyses (7)

Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed

Related Experiments (1)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (8)

BACE1 (Redirect)
redirect · KG edge: associated_with
astrocyte-neuron-metabolic-coupling-parkinsons
general · KG edge: transports
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: associated_with
AQP4 (Aquaporin-4 Gene)
gene · KG edge: activates
APOE contributes to Alzheimer's disease by regulating b
hypothesis · KG edge: debate_co_mention

Knowledge Graph (12 edges)

MAX inhibits CGAS
MAX inhibits STING
MAX inhibits PARP1
MAX inhibits IRF3
DRP1 regulates MAX
TOMM20 regulates MAX
MAX regulates MIRO1
MAX regulates MID51
MAX regulates MID49
MAX regulates MFF

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