| Gene Symbol | LIS1 |
| Full Name | Lissencephaly 1 (PAFAH1B1) |
| Aliases | LIS1PROTEIN |
| Chromosome | 17p13.3 |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Molecular Weight | 46 kDa |
| UniProt ID | [P43004](https://www.uniprot.org/uniprot/P43004) |
| Ensembl ID | ENSG00000007174 |
| GeneCards | LIS1 |
| Human Protein Atlas | LIS1 |
| N-terminal dimerization domain | forms functional dimers |
| Dynein binding site | engages dynein heavy chain |
| Phosphorylation sites | regulatory control |
| Nistrin homology domain | unique to LIS1 family |
| Dynein regulation | modulates dynein motor activity |
| Associated Diseases | AD, ADH, ALI, Als, AMI |
| Interactions | Actin, AND, CDK5, DAB1, DISC1, Dynein |
| KG Connections | 51 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!
No comments yet. Be the first to comment!