| Gene Symbol | LC3PROTEIN |
| Full Name | Microtubule-Associated Protein 1 Light Chain 3 |
| Function | is a fundamental protein in the autophagy pathway and serves as a key marker for autophagosome formation. |
| Primary Expression | various tissues - LC3B (MAP1LC3B) - the most studied isoform, commonly used as an autophagy marker - LC3C (MAP1LC3C) - more restricted express |
| Molecular Weight | ~17 kDa |
| UniProt ID | Q9GZF4 (LC3A), Q9GZY8 (LC3B) |
| GeneCards | LC3PROTEIN |
| Human Protein Atlas | LC3PROTEIN |
| GABARAP** and **GATE-16 | related proteins in the ATG8 family[@shpilka2021] |
| Associated Diseases | AD, Aging, ALI, Als, Alzheimer |
| Known Drugs/Compounds | ATTECs, CISPLATIN, dimethyl fumarate, licorice, nicotinamide, rapamycin |
| Interactions | 6-OHDA, ABCA1, ABCD3, ABCG1, ABP, ACAT1 |
| KG Connections | 3246 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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