| Gene Symbol | LAMP3 |
| Full Name | Lysosomal Associated Membrane Protein 3 |
| Chromosome | 3q27.2. |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | mature dendritic cells and plays critical roles in: - MHC class II antigen presentation: Colocalizes with MHC class II compartments - Immune syn |
| Subcellular Localization | </strong></td><td>Lysosomes, Late Endosomes, Cell Surface (dendritic cells)</td></tr> |
| Molecular Weight | 61.7 kDa |
| UniProt ID | [Q9UQ15](https://www.uniprot.org/uniprot/Q9UQ15) |
| Ensembl ID | ENSG00000046651 |
| GeneCards | LAMP3 |
| Human Protein Atlas | LAMP3 |
| Lumenal domain | Large heavily glycosylated region containing multiple N-linked glycosylation sites (up to 29 potential sites) |
| Transmembrane domain | Single pass alpha-helical segment |
| Cytoplasmic tail | Short tail containing trafficking signals (YXXφ motif) |
| MHC class II antigen presentation | Colocalizes with MHC class II compartments |
| Associated Diseases | neurodegeneration |
| KG Connections | 9 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!