| Gene Symbol | LAMP3 |
| Full Name | Lysosomal Associated Membrane Protein 3 |
| Chromosome | 3q27.2. |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | mature dendritic cells and plays critical roles in: - MHC class II antigen presentation: Colocalizes with MHC class II compartments - Immune syn |
| Molecular Weight | 61.7 kDa |
| UniProt ID | [Q9UQ15](https://www.uniprot.org/uniprot/Q9UQ15) |
| Ensembl ID | ENSG00000046651 |
| GeneCards | LAMP3 |
| Human Protein Atlas | LAMP3 |
| Lumenal domain | Heavily glycosylated with multiple N-glycosylation sites |
| Transmembrane region | Single pass membrane protein |
| Cytoplasmic tail | Contains lysosomal targeting motifs |
| Dendritic cell maturation | DC-LAMP is a marker of mature dendritic cells |
| Antigen presentation | May contribute to neuroinflammation |
| Associated Diseases | neurodegeneration |
| KG Connections | 9 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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