| Gene Symbol | KAT2B |
| Full Name | Lysine Acetyltransferase 2B (PCAF) |
| Aliases | Lysine Acetyltransferase 2B |
| Chromosome | 3p24.3 |
| Protein Type | Transferase |
| Function | KAT2B (also known as PCAF - p300/CBP-associated factor) encodes a histone acetyltransferase that plays a crucial role in transcriptional regulation through chromatin remodeling. |
| Primary Expression | various brain regions and cell types, where it contributes to synaptic transmission, gene regulation, and intracellular signaling cascades |
| Subcellular Localization | </strong></td><td>Nucleus</td></tr> |
| Pathways | Autophagy |
| UniProt ID | [Q92830](https://www.uniprot.org/uniprot/Q92830) |
| Ensembl ID | ENSG00000114166 |
| OMIM | 602303 |
| GeneCards | KAT2B |
| Human Protein Atlas | KAT2B |
| Neurodevelopmental disorders | Altered histone acetylation during brain development |
| Associated Diseases | Parkinson, Tumor |
| Known Drugs/Compounds | rapamycin |
| Interactions | ACAT1, AMPK, ATG, CBP, CREB, GSK3 |
| KG Connections | 192 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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