| Gene Symbol | GBM |
| Full Name | Glioma-Associated Oncogene Homolog |
| Aliases | GBMPROTEIN |
| Chromosome | 3p25.1 |
| Protein Family | C2H2-type zinc finger transcription factors |
| Exons | 14 |
| Pathways | Amyloid, Angiogenesis, Apoptosis, Autophagy, Blood-Brain Barrier |
| UniProt ID | P08151 |
| NCBI Gene ID | 2735 |
| Ensembl ID | ENSG00000087495 |
| GeneCards | GBM |
| Human Protein Atlas | GBM |
| EGFR Amplification | Epidermal Growth Factor Receptor gene amplification occurs in ~40% of primary GBM cases, leading to constitutive activation of proliferative signaling pathways[@furnari2007] |
| PTEN Loss | Phosphatase and tensin homolog deletion is found in ~30-40% of cases |
| TP53 Mutations | Tumor protein p53 mutations are common, particularly in secondary GBM |
| Associated Diseases | AD, Aging, ALI, Als, Alzheimer |
| Known Drugs/Compounds | quercetin, SSRI |
| Interactions | Actin, AIM2, AKT, ALZHEIMER, ALZHEIMER'S DISEASE, AMPK |
| KG Connections | 1349 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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