protein 1,236 words KG: GABAARECEPTORTHETAPROTEIN
Contents

GABA-A Receptor Theta (GABRQ) Protein

🔬 Protein Info
Gene SymbolGABA
Full NameA Receptor Theta (GABRQ) Protein
Chromosome12p12.3
Functionis a hallmark of neurodegeneration.
Primary Expressionhippocampus, cortex, cerebellum, thalamus, hypothalamus
Subcellular LocalizationPlasma membrane, postsynaptic and extrasynaptic
Molecular Weight~56 kDa
Amino Acids602 aa
Exons14
PathwaysGABAergic Signaling
UniProt IDQ9UII2
GeneCardsGABA
Human Protein AtlasGABA
Protein NameGABRQ (GABA-A Receptor Theta)
GeneGABRQ
Associated DiseasesAls, Alzheimer, Alzheimer's disease
Known Drugs/Compoundsrapamycin
InteractionsABCA7, ACTB, Actin, Akt, AKT, AKT1
KG Connections1369 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

Agent Input

Related Hypotheses (7)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.38
Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.86
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.72
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62
Biorhythmic Interference via Controlled Sleep Oscillations
Score: 0.66

Related Analyses (10)

What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Related Experiments (3)

Metabolic Pathway-Targeted Therapy in ALS
clinical · proposed · Score: 0.40
Experiment: Autoimmune Hypothesis Testing in AD
clinical · proposed · Score: 0.40
Non-Dopaminergic Neurotransmitter Degeneration in PD - Exper
clinical · proposed · Score: 0.40

See Also (3)

TREK1 Neurons
cell · KG edge: binds
Neurodegeneration
disease · KG edge: implicated_in
GABRR3 Gene
gene · KG edge: binds

Knowledge Graph (2 edges)

GABRR3 binds GABAARECEPTORTHETAPROTEIN
GABAARECEPTORTHETAPROTEIN binds TREK1

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